• Produced principally by Pineal Gland. Small amount is secreted by GastroIntestinal Tract and Skin.
  • Daily estimated secretion is 30-100 mcg.
  • Highest level of Melatonin are observed at night and are due to an intense production by Pineal gland during sleep.
  • The lowest level of Melatonin are found during the day. The day time secretion is mainly by the Gastrointestinal Tract and Skin.
  • Melatonin levels decrease with Aging.
  • Melatonin Induces Sleep.
  • Melatonin shortens the time to fall asleep.
  • Melatonin has no action on deep sleep and REM.
  • At night, Melatonin induces profound relaxation of nerves and muscles, which makes the sleep better.
  • Melatonin acts as an antispasmodic for the intestinal tract, relaxing it when it is contracted and tensed.
  • Melatonin protects against free radicals by its antioxidant properties.
  • Melatonin has Antiaging properties.
  • Melatonin boosts Immune functions.
  • Melatonin helps in setting the pace for circadian rhythms such as sleep-wake, temperature and hormones cycles.
  • Melatonin prevents against Jet-Lag.
  • Melatonin can increase the serum levels of Growth Hormone.
  • Melatonin increases the conversion of T4 to T3.
  • Melatonin calms down excessive cortisol activity.

Indications For Melatonin Replacement

  • Circadian Rhythm disorders like JET-LAG.
  • Stress
  • Mood disorders
  • CVA
  • Sleep disorders
  • Immune disorders
  • Component of Menopause HRT
  • Component of Andropause HRT
  • Component of Somatopause HRT
  • Component of Adrenopause HRT
  • Age associated mental decline
  • As anti-oxidant
  • As Immunity Enhancer in various Immunodeficiency states
  • Fibromyalgia
  • Skin Aging
  • Supportive therapy in anti-cancer management
  • Supportive therapy in Alzheimer's disease

Questionnaires

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    Test yourself for Melatonin Deficiency (Both Men & Women)

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